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You are here: Research & Tech Bee Health Genome Sequence of Paenibacillus larvae - the bacillus causing AFB in Honey Bees - Updated

Genome Sequence of Paenibacillus larvae - the bacillus causing AFB in Honey Bees - Updated

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Pune, September 17, 2011: Soon after the Apis mellifera genome sequence was studied, investigations on genomes of honey bee pathogens, like Paenibacillus larvae, Nosema ceranae and Ascosphaera apis have been taken up. Qin and four other researchers from the Human Genome Sequencing Center, Houston, Texas, Bee Research Laboratory, USDA, Beltsville, Maryland and the Honey Bee Unit, USDA, Weslaco, Texas, USA have in 2006 reported1 genome sequence of Paenibacillus larvae, the pathogen causing American foulbrood disease in honey bees.

Chan and eleven other researchers from the University of British Columbia, Vancouver, British Columbia Cancer Agency, Vancouver, Canada, Bee Research Laboratory, USDA, Beltsville, Maryland, USA and Ghent University, Kiel, Germany have in a paper2 published in the journal BMC Genomics on September 16, 2011 provided an update of the genome of the bacillus species. The authors say: "This update on the genome of P. larvae and annotation represents an immense advancement from what we had previously known about this species. We provide here a reliable resource that can be used to elucidate the mechanism of infection, and by extension, more effective methods to control and cure this widespread honey bee disease."

An abstract of the paper can be seen here, and a provisional version of the full paper can be seen here.

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References cited:

1. Qin, X., Evans, J.D., Aronstein, K.A. Murray, K.D. and Weinstock, G.M. 2006. Genome sequences of the honey bee pathogens Paenibacillus larvae and Ascosphaera apis. Insect Molecular Biology 15 (5): 715-718.

2. Chan, Q.W.T., Cornman, R.S., Birol, I., Liao, N.Y., Chan, S.K., Docking, T.R., Jackman, S.D., Taylor, G.A., Jones, S.J.M., de Graaf, D.C., Evans, J.D. and Foster, L.J. 2011. Updated genome assembly and annotation of Paenibacillus larvae, the agent of American foulbrood disease of honey bees. BMC Genomics 12: 450. doi:10.1186/1471-2164-12-450